In an appearance on The Joe Rogan Experience, neuroscientist Dr. Andrew Huberman talked about NAD supplementation and peptide research.
Huberman explained the recent controversy surrounding NMN (nicotinamide mononucleotide), a popular NAD precursor.
“NAD is critical to energy production in all cells, vital,” he stated. “Levels of NAD tend to go down as we age. It’s an absolute requirement for cellular health and life. You need it.”
The discussion centered on how NMN supplementation became caught in regulatory crosshairs.
According to Huberman, “They’re studying something similar to NMN, it’s a slight variation on NMN, and it’s an experimental d**g. The way the FDA works is if something is being explored as an experimental potential prescription d**g or pharmaceutical compound, it cannot be sold as a supplement.”
This created controversy because, as Huberman noted, “A lot of people are inflamed because this thing was popularized through the discussion of NMN and its potential virtues, and then now the FDA sent out a ruling early this year that supplement companies cannot sell it.”
Huberman shared his personal protocol and results with NMN. “I personally take about two grams per morning under my tongue,” he explained, noting a definite subjective increase in energy.
He emphasized the sublingual route, explaining that taking capsules may not be as effective for cellular absorption.
His experience included notable changes: “My recovery from workouts was much better. I had to take it early in the day because it was giving me a lot of energy… I did notice my hair and nails growing at a ridiculous rate. Then I came off it just as a control experiment and it slowed down again.”
He stressed the importance of public advocacy, urging listeners that “if you’re interested in keeping NMN or anything on the market, write letters… In the absence of those letters, there’s no chance of things going the way you want.”
